The Structural Informatics Unit (SIU) seeks to elucidate the molecular architecture, function, and epitope diversity of viral proteins. The research program exploits 3D electron microscopy of viruses and protein complexes to obtain structural information. Structural analyses are supported by other structural, biochemical, and immunological analyses in order to understand antigen-antibody interactions and aid in both structure-assisted immunogen and therapeutic designs for infectious diseases. Our research program integrates structural, biochemical and immunogenicity studies with bioinformatics to facilitate a collaborative synergy between these disciplines in the context of the focus on structure-function studies of viruses and viral proteins. A major focus is on the antigenicity, structure, and function of respiratory viruses, such as influenza. We are looking for candidates who can work collaboratively on problems related to virus structure, assembly, immunology and vaccine development.
Candidates should have a strong background in at least one of these areas: structural biology (cryo-electron microscopy or x-ray crystallography), computational biology/image or data processing. Also, candidates with backgrounds in areas such as immunology, virology, protein biochemistry, vaccine development and animal studies are strongly encouraged to apply.
Applicants must have a Ph.D., or M.D., or equivalent, and less than 5 (preferably have less than 2) years of postdoctoral experience.
Candidates should submit a CV, and a one-page research experience summary describing research accomplishments, and contact information for three letters of reference. Please write “Postdoctoral application” in the subject header and send to: Audray K. Harris, Ph.D., Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 50 South Drive, Room 6351, MSC 8005, Bethesda, MD 20892-8005 USA or email the documents to firstname.lastname@example.org. Positions will remain open until filled.
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